Connectivity Map

Connectivity Map. Global Network Connection. World Map Point and Line Composition Concept The ultimate objective of biomedical research is to connect human diseases with the genes that underlie them and drugs that treat them The Connectivity Map: using gene-expression signatures to connect small molecules, genes, and disease

Worldwide Network Connection. Stock Vector Illustration of modern
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This web interface is designed to allow biologists. The Broad Institute's Connectivity Map is a collection of genome-wide, transcriptional expression data from cultured human cells

Worldwide Network Connection. Stock Vector Illustration of modern

The Connectivity Map: using gene-expression signatures to connect small molecules, genes, and disease The Connectivity Map: using gene-expression signatures to connect small molecules, genes, and disease The Connectivity Map is a collection of genome-wide transcriptional expression data from cultured human cells treated with bioactive small molecules and simple pattern-matching algorithms that together enable the discovery of decisive functional connections between drugs, genes, and diseases

Network Mapping. The Connectivity Map: using gene-expression signatures to connect small molecules, genes, and disease But this remains a daunting task, and even the most inspired researchers still have to resort to laborious screens of genetic or chemical libraries.

Economic Contribution. We demonstrate that this "Connectivity Map" resource can be used to find connections among small molecules sharing a mechanism of action, chemicals and physiological processes, and diseases and drugs The Connectivity Map is the most comprehensive effort yet for using genomics in a drug-discovery framework